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Updated: Jun 2, 2026

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
Published on: December 4, 2016
An electroneutral macrocyclic iron(II) complex that enhances MRI contrast in vivo
Fayçal Touti1, Akhilesh Kumar Singh, Philippe Maurin
1Laboratoire de Chimie, UMR 5182 CNRS, Ecole Normale Superieure de Lyon, Lyon, France.
Abstract:
The first example of a macrocyclic ferrous complex, where two tetrazolyl pendent arms compensate the charge of the metal center, is synthesized and examined for its capacity to enhance MRI contrast in vitro and in vivo in the mouse.
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