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Perioperative blood pressure variability in patients undergoing coronary artery bypass grafting: its magnitude and

Lukasz J Krzych1, Michał Krejca, Jarosław Bis

  • 1First Departments of Cardiac Surgery, Medical University of Silesia, Katowice, Poland. l.krzych@wp.pl

Blood Pressure Monitoring
|May 13, 2011
PubMed

Insights

Perioperative blood pressure variability during coronary artery bypass grafting (CABG) is significant, especially during extracorporeal circulation (ECC). Healthier patients, including younger ones and women, exhibit greater BP lability, requiring careful anesthetic management.

Area of Science:

  • Cardiovascular Surgery
  • Anesthesiology
  • Critical Care Medicine

Background:

  • Perioperative blood pressure (BP) management is critical during coronary artery bypass grafting (CABG).
  • Extracorporeal circulation (ECC) significantly impacts hemodynamic stability.
  • Understanding BP variability determinants is crucial for optimizing patient outcomes.

Purpose of the Study:

  • To quantify perioperative blood pressure variability in CABG patients undergoing ECC.
  • To identify factors influencing BP variability, including patient demographics and comorbidities.

Main Methods:

  • Direct intraoperative BP measurement via radial artery cannula in 200 CABG patients.
  • BP recorded every 5 minutes across three surgical phases: pre-ECC, during ECC, and post-ECC.
  • BP variability assessed using coefficient of variation for systolic, diastolic, mean, and pulse pressures.

Main Results:

  • Greatest BP variability observed during ECC, particularly for pulse pressure.
  • Diastolic BP showed greater percentage changes than systolic BP.
  • Higher BP lability noted in women, younger patients, and those without diabetes, hypertension, or obesity.

Conclusions:

  • Perioperative anesthetic management requires attention to both complex and healthier patient groups.
  • Younger and healthier patients undergoing CABG exhibit greater BP variations.
  • Tailored anesthetic strategies are necessary to manage BP lability in diverse patient profiles.
Abstract

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