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Updated: Jun 2, 2026

Measuring the Behavioral Effects of Intraocular Scatter
Published on: February 18, 2021
Quantitative evaluation of night vision and correlation of refractive and topographical parameters with glare after
Takashi Kojima1, Asato Hasegawa, Syuya Hara
1Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan. tkojkoj@mac.com
Purpose:
To evaluate night vision disturbance and investigate correlations between pre- and post-treatment parameters and glare scores in orthokeratology patients.
Methods:
Twenty-eight right eyes of 28 patients were enrolled in this study. Corneal topography and a night vision test (NVT) to evaluate the extent of glare were performed after orthokeratology. From the corneal topography, two indices [surface regularity index (SRI) and surface asymmetry index (SAI)] were calculated. Fourier analysis was performed on the topographic data from the central 6 mm, and data were decomposed into asymmetric and higher order components for analysis.
Results:
There was no correlation between the glare score and pre-treatment keratometric value, pre-treatment cylinder, post-treatment sphere, and post-treatment cylinder. However, there was a statistically significant correlation between pre-treatment sphere and glare score (Pearson correlation coefficient, r = -0.54, p < 0.01). SRI and SAI significantly correlated with glare score (SRI: r = 0.52, p < 0.01, SAI: r = 0.41, p < 0.05). Higher order and asymmetric components were also significantly correlated with glare score (asymmetry: r = 0.61, p < 0.01, higher order: r = 0.67, p < 0.001).
Conclusions:
The glare score was significantly correlated with corneal irregularity, and appeared to be a beneficial parameter for assessment of night vision performance in patients receiving orthokeratology.
