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Updated: Jun 2, 2026
05:25
Simultaneous Detection of Different Antibody Classes in a Multiplexed Serological Test
Published on: July 14, 2023
['Specificity' in microbiology and immunochemistry between 1880 and 1930].
1Sezione di Storia della medicina, Sapienza-Università di Roma, Italy. gilberto.corbellini@gmail.com
Medicina Nei Secoli
|May 14, 2011
Summary
The late 19th century saw major advances in microbiology and immunochemistry, revealing microbial biochemical properties and their role in infectious diseases. Research established that microbial specificity drives biological phenomena and immune reactions depend on biochemical molecules.
Area of Science:
- Microbiology
- Immunochemistry
- Biochemistry
Context:
- The late 19th century marked a transformative period for microbiological sciences.
- Acquisition of new conceptual, methodological, and technological tools revolutionized the understanding of microorganisms.
- Focus shifted to microbial biochemical properties and their role in infectious diseases.
Purpose:
- To investigate the nature and characteristics of microbes, both pathogenic and non-pathogenic.
- To explore the origins of chemical properties in immune sera.
- To explain the morphological, physiological, and pathogenetic differences among microbial species.
Summary:
- Research between 1880 and 1930 demonstrated that microbial specificity is fundamental to biological phenomena.
- Studies revealed that immune reactions are dictated by the biochemical properties of specific molecules.
- These molecules, produced by physiological systems, recognize and react against foreign substances.
Impact:
- Established the biochemical basis of microbial specificity and immune responses.
- Laid the groundwork for modern understanding of infectious diseases and immunology.
- Advanced the fields of microbiology, immunochemistry, and biochemistry through empirical and theoretical research.
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