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Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Hypodermis01:02

Hypodermis

The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

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Related Experiment Video

Updated: Jun 2, 2026

Localization, Identification, and Excision of Murine Adipose Depots
08:53

Localization, Identification, and Excision of Murine Adipose Depots

Published on: December 4, 2014

Obesity and the skin.

A R Shipman1, G W M Millington

  • 1Department of Dermatology, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich NR4 7UY, UK.

The British Journal of Dermatology
|May 14, 2011
PubMed
Summary
This summary is machine-generated.

Obesity is a major global health concern linked to various health issues, including skin conditions. This review covers common and rare dermatological problems associated with excess body weight and its treatments.

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Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

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Last Updated: Jun 2, 2026

Localization, Identification, and Excision of Murine Adipose Depots
08:53

Localization, Identification, and Excision of Murine Adipose Depots

Published on: December 4, 2014

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Area of Science:

  • Dermatology
  • Public Health
  • Endocrinology

Background:

  • Obesity is a significant global health challenge with widespread implications.
  • Excess body weight is implicated in carcinogenesis and the pathogenesis of metabolic, cardiovascular, and musculoskeletal disorders.
  • Obesity presents numerous cutaneous manifestations, impacting patient health and quality of life.

Purpose of the Study:

  • To review the cutaneous features associated with obesity.
  • To discuss common and rare dermatological conditions linked to excess body weight.
  • To explore the dermatological side-effects of obesity interventions.

Main Methods:

  • Literature review of studies on obesity and dermatological conditions.
  • Analysis of common skin issues in obese individuals.
  • Examination of rarer skin disorders and inflammatory dermatoses in obesity.
  • Review of dermatological side-effects of obesity treatments.

Main Results:

  • Common cutaneous features include striae distensae, plantar hyperkeratosis, and increased susceptibility to skin infections.
  • Obesity is associated with impaired wound healing, malignant melanoma risk, and inflammatory dermatoses like psoriasis.
  • Obesity management strategies, including medications and surgery, can cause dermatological side-effects.

Conclusions:

  • Obesity is linked to a spectrum of dermatological conditions, ranging from common to rare.
  • Understanding these cutaneous manifestations is crucial for comprehensive obesity management.
  • Healthcare providers must consider potential skin issues and treatment side-effects in obese patients.