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Related Experiment Video

Updated: Oct 16, 2025

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Published on: April 21, 2019

Issues surrounding consumer-bought food-allergy testing.

A W Y Wong¹, H E G White¹, A Plant¹

¹Department of Dermatology, Portsmouth Hospital, Portsmouth, UK.

Clinical and Experimental Dermatology

|October 16, 2021

Summary

This summary is machine-generated.

Direct-to-consumer (DTC) allergy tests are often misleading, using unaccredited labs and unvalidated methods. Rely on clinical history and specific IgE testing for accurate food allergy diagnosis.

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Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

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Published on: September 14, 2018

Area of Science:

Immunology
Dermatology
Consumer Health

Background:

Increasing prevalence of reported allergies.
Rise of direct-to-consumer (DTC) allergy tests available online.
Concerns regarding the diagnostic accuracy of non-clinician-led allergy testing.

Purpose of the Study:

Evaluate the accreditation and methodologies of DTC allergy tests.
Assess the clinical validity of DTC allergy testing processes.
Provide an overview of available online DTC allergy tests.

Main Methods:

Conducted internet searches for "allergy test kit" and "intolerance test".
Contacted companies to inquire about ISO15189 accreditation, testing methods, and clinical input.
Identified 24 DTC food allergy testing companies, with 22 contactable.

Main Results:

Only one laboratory possessed ISO15189 accreditation.
This accredited lab was the sole user of specific IgE testing with clinician involvement.
Other labs utilized controversial methods like bioresonance or IgG testing, with limited nutritionist input.

Conclusions:

Most online DTC food allergy tests are misleading due to unaccredited labs and unvalidated methods.
Dermatologists should disregard DTC test results and focus on clinical history.
Specific IgE testing, when clinically indicated, is the recommended approach for diagnosing food allergies.