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Mapping Metabolism: Monitoring Lactate Dehydrogenase Activity Directly in Tissue
Published on: June 21, 2018
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Lactate dehydrogenase in dermatology practice
A Livesey1, F Garty1, A R Shipman1
1Dermatology Department, St Mary's Hospital, Portsmouth, UK.
Clinical and Experimental Dermatology
|November 23, 2019
Abstract:
Lactate dehydrogenase (LDH) is used in dermatology practice, particularly as a prognostic marker for cutaneous lymphoma. LDH is an intracellular enzyme involved in anaerobic glycolysis, and is found at low concentrations in the blood. LDH is produced in every tissue, thus cell damage releases LDH into the circulation, so the causes of elevated LDH levels are multiple. The utility of LDH in dermatology practice is reviewed, alongside current diagnostic and staging guidelines.

