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Indel Detection following CRISPR/Cas9 Mutagenesis using High-resolution Melt Analysis in the Mosquito Aedes aegypti
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Indel Detection following CRISPR/Cas9 Mutagenesis using High-resolution Melt Analysis in the Mosquito Aedes aegypti

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Characterization of eight single nucleotide polymorphism markers in Aedes aegypti

Ks Paduan1, Pem Ribolla

  • 1Departamento de Parasitologia, Instituto de Biociências, Universidade Estadual Paulista, Caixa Postal 510, 18618-000, Botucatu, São Paulo, Brazil.

Molecular Ecology Resources
|May 14, 2011
PubMed

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Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...