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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Whole Vitreous Humor Dissection for Vitreodynamic Analysis
04:41

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Published on: May 24, 2015

Utility values associated with vitreous floaters.

Ajeet M Wagle1, Wei-Yen Lim, Tiong-Peng Yap

  • 1Department of Ophthalmology and Visual Sciences, Khoo Teck Puat Hospital, Singapore. wagle.ajeet.madhav@alexandrahealth.com.sg

American Journal of Ophthalmology
|May 17, 2011
PubMed
Summary
This summary is machine-generated.

Symptomatic degenerative vitreous floaters negatively impact quality of life. Younger patients with floaters are more willing to risk blindness to remove them compared to older patients.

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Area of Science:

  • Ophthalmology
  • Quality of Life Research
  • Health Economics

Background:

  • Degenerative vitreous floaters are common, causing visual disturbances.
  • The impact of floaters on health-related quality of life (HRQoL) requires further investigation.

Purpose of the Study:

  • To ascertain the health-related quality of life associated with symptomatic degenerative vitreous floaters.
  • To evaluate patient preferences regarding risk tolerance for floater removal.

Main Methods:

  • Cross-sectional questionnaire survey of 266 outpatients with symptomatic floaters.
  • Utility values assessed using Time Trade-Off (TTO) and Standard Gamble (SG) techniques.
  • Descriptive, univariate, and multivariate analyses performed.

Main Results:

  • Mean utility values were 0.89 (TTO), 0.89 (SG-death), and 0.93 (SG-blindness).
  • Younger patients (≤55 years) reported significantly lower SG (blindness) utility values.
  • No significant relationship found between utility values and socio-demographic or ocular characteristics.

Conclusions:

  • Symptomatic degenerative vitreous floaters significantly impair HRQoL.
  • Younger symptomatic patients exhibit a higher risk tolerance for blindness to achieve floater relief.