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Pre-admission CHADS2 score is related to severity and outcome of stroke

Shoichiro Sato1, Yukako Yazawa, Ryo Itabashi

  • 1Department of Stroke Neurology, Kohnan Hospital, Sendai, Japan. stshoh@gmail.com

Journal of the Neurological Sciences
|May 17, 2011
PubMed

Insights

The pre-admission CHADS(2) score predicts stroke severity and outcomes in atrial fibrillation (AF) patients. Higher scores correlate with worse stroke severity (NIHSS) and increased mortality risk.

Area of Science:

  • Cardiology
  • Neurology
  • Stroke Medicine

Background:

  • The CHADS(2) score is a standard tool for stratifying stroke risk in patients with atrial fibrillation (AF).
  • Understanding the correlation between pre-admission risk scores and actual stroke outcomes is crucial for patient management.

Purpose of the Study:

  • To investigate the relationship between the pre-admission CHADS(2) score and stroke severity.
  • To assess the association between the CHADS(2) score and stroke outcomes in patients with AF-related cardioembolic stroke.

Main Methods:

  • A retrospective review of 423 consecutive patients with AF-related cardioembolic stroke.
  • Analysis of pre-admission CHADS(2) scores, National Institutes of Health Stroke Scale (NIHSS) scores on admission, and modified Rankin Scale (mRS) scores at discharge.

Main Results:

  • Significant correlations were found between CHADS(2) scores and both NIHSS (stroke severity) and mRS (stroke outcome) scores.
  • An optimal CHADS(2) cutoff score of ≥2 predicted an mRS score ≥3 (poor outcome), and a score of ≥3 predicted death.
  • Multivariate analysis confirmed that CHADS(2) scores ≥2 and ≥3 were independent predictors of poor outcome and death, respectively.

Conclusions:

  • The pre-admission CHADS(2) score is a valuable predictor of stroke severity and patient outcomes in individuals with atrial fibrillation.
  • These findings support the utility of the CHADS(2) score beyond initial stroke risk assessment, extending to post-stroke evaluation.
Abstract

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