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Related Concept Videos

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Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
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Sexually Transmitted Infections

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Peptic Ulcer Disease III: Clinical Manifestations and Complications01:25

Peptic Ulcer Disease III: Clinical Manifestations and Complications

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Updated: Jun 2, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

Chronic genital ulceration: a 'topical' issue.

S Schoeman1, S Sommer, E F Monteiro

  • 1Centre for Sexual Health, Leeds Teaching Hospitals NHS Trust, UK. sarah.schoeman@leedsth.nhs.uk

International Journal of STD & AIDS
|May 17, 2011
PubMed
Summary
This summary is machine-generated.

A man developed a chronic penile ulcer from repeatedly applying crushed paracetamol tablets topically. This unusual case highlights a rare adverse effect of self-medication with common pain relievers.

Related Experiment Videos

Last Updated: Jun 2, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

Area of Science:

  • Urology
  • Dermatology
  • Pharmacology

Background:

  • Topical medications are widely used for various conditions.
  • Paracetamol (acetaminophen) is a common over-the-counter analgesic and antipyretic.
  • Self-medication practices can lead to unforeseen adverse effects.

Observation:

  • A case of a chronic, non-healing penile ulcer is presented.
  • The ulcer resulted from the repeated topical application of crushed paracetamol tablets.
  • This represents a unique presentation not previously documented in medical literature.

Findings:

  • Chronic topical paracetamol application can cause severe localized tissue damage.
  • The mechanism may involve direct chemical irritation or other unknown factors.
  • Penile skin is particularly susceptible to such iatrogenic injury.

Implications:

  • Clinicians should inquire about topical medication use in non-healing wounds.
  • Patient education regarding safe medication practices is crucial.
  • Further research may be needed to understand the specific pathophysiology of paracetamol-induced skin ulceration.