Related Experiment Video
Updated: Jun 2, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Pediatric vitamin D deficiency in a southwestern luminous climate
Elizabeth Ann Szalay1, Elyce B Tryon, Michael D Pleacher
1Department of Orthopaedics, University of New Mexico School of Medicine, UNM Carrie Tingley Hospital, 1127 University Blvd. NE, Albuquerque, NM 87102, USA. ESzalay@salud.unm.edu
Insights
Even in sunny climates, many children have insufficient vitamin D levels. This study found that 14% of children had vitamin D levels below 20 ng/mL, indicating a need for supplementation.
Area of Science:
- Pediatrics
- Endocrinology
- Nutritional Science
Background:
- Vitamin D sufficiency is often assumed in sunny climates due to sun exposure.
- Changing lifestyles may impact vitamin D levels in children.
- Previous studies highlighted vitamin D deficiency in extreme climates.
Purpose of the Study:
- To examine vitamin D levels in healthy children residing in a sunny climate.
- To assess if children with vague musculoskeletal pain have different vitamin D levels compared to healthy controls.
Main Methods:
- Retrospective chart review of vitamin D levels in children with musculoskeletal pain.
- Prospective recruitment of healthy children without pain as controls.
- Analysis of vitamin D levels (ng/mL) in 88 children (42 pain, 46 controls).
Main Results:
- No significant difference in vitamin D levels between the pain group (29.1 ng/mL) and control group (32.4 ng/mL).
- Overall, 14% of children had vitamin D levels <20 ng/mL (insufficient).
- 49% of children had vitamin D levels <30 ng/mL, a potentially desired level.
Conclusions:
- A sunny climate does not guarantee vitamin D sufficiency in children.
- A significant percentage of children in this study had insufficient or suboptimal vitamin D levels.
- Universal vitamin D supplementation is suggested for children, with monitoring for high-risk individuals.
Background:
Few studies look at vitamin D levels in children living in sunny climates as it is assumed that they receive adequate vitamin D from sun exposure. In light of changing lifestyles of children and studies documenting vitamin D deficiency among children in extreme climates, a study to examine vitamin D levels in healthy children living in a luminous climate was conducted.
Methods:
A retrospective chart review of vitamin D levels in healthy children with vague musculoskeletal pain (such as "growing pains") was done. Healthy children, specifically without musculoskeletal pain, were prospectively recruited as controls.
Results:
Eighty-eight children, 42 children with "pain" and 46 controls were studied. No statistical difference in vitamin D levels was found between the "pain" group (mean vitamin D level 29.1 ng/mL) and the control group (mean vitamin D level 32.4 ng/mL, P<0.52). Overall, 14% of the entire group had levels <20 ng/mL, 49% had levels <30 ng/mL, and 15% had levels >40 ng/mL.
Conclusions:
A consensus has yet to be established as to what an "optimal" vitamin D level is for growing children to develop strong bones for a lifetime. This study demonstrated that 14% of children living in a sunny climate had vitamin D levels below 20 ng/mL, a level universally accepted as insufficient, and 49% were below 30 ng/mL, arguably a "desired" level. A sunny climate does not assure vitamin D sufficiency. Virtually all children should be supplemented, with laboratory follow-up for those at high risk for low bone density/those with insufficiency fractures.
More Related Videos
Related Concept Videos
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Pharmacokinetics in Pediatric Patients: Drug Excretion
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pigmentation
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Drug Dosing: Infants and Children
