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Related Experiment Video

Updated: Jun 2, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
08:50

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

Chorioamnionitis due to Arcanobacterium haemolyticum.

Sonal Saxena1, Charu Aggarwal, Anuradha

  • 1Department of Microbiology, Lady Hardinge Medical College, New Delhi, India.

Journal of Global Infectious Diseases
|May 17, 2011
PubMed
Summary

This case report details chorioamnionitis caused by Arcanobacterium haemolyticum, an uncommon pathogen. Prompt diagnosis and treatment are crucial for managing this serious pregnancy infection.

Keywords:
Arcanobacterium haemolyticumChorioamnionitisPremature rupture of membranes

Related Experiment Videos

Last Updated: Jun 2, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
08:50

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Microbiology

Background:

  • Chorioamnionitis is a common intra-amniotic infection, typically caused by ascending vaginal flora or hematogenous spread.
  • It poses significant risks for maternal and fetal mortality and morbidity.
  • Early diagnosis and appropriate antibiotic therapy are essential for favorable outcomes.

Observation:

  • A 19-year-old primigravida at 32 weeks gestation presented with symptoms of chorioamnionitis, including fever and vaginal discharge.
  • Arcanobacterium haemolyticum was identified as the causative agent in the amniotic fluid.
  • The patient received a course of gentamicin and metronidazole.

Findings:

  • A healthy male infant weighing 1.9 kg was delivered following induction of labor.
  • The mother experienced an uneventful recovery and was discharged on the ninth postpartum day.
  • Isolation of Arcanobacterium haemolyticum highlights the diverse microbial causes of chorioamnionitis.

Implications:

  • This case underscores the importance of considering unusual pathogens in chorioamnionitis diagnosis.
  • Increased awareness among clinicians and laboratory personnel can prevent misdiagnosis.
  • Timely and accurate identification of causative agents facilitates targeted antimicrobial treatment, improving patient outcomes.