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Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation
09:30

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Published on: March 4, 2016

A Review of Non-cultured Epidermal Cellular Grafting in Vitiligo

Nanja van Geel1, Boon Kee Goh, Elien Wallaeys

  • 1Department of Dermatology, Ghent University Hospital, De Pintelaan, Ghent, Belgium.

Journal of Cutaneous and Aesthetic Surgery
|May 17, 2011
PubMed

Keywords:
Melanocyte transplantationcellular graftingsurgical treatmentvitiligo

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...