Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's criteria,...
Pleura of the Lungs01:13

Pleura of the Lungs

The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reply: Timing, risk, and relevance: Refining venous thromboembolism screening in esophageal cancer.

The Journal of thoracic and cardiovascular surgery·2026
Same author

Integrating adjuvant therapy as standard multimodal treatment for patients with esophageal cancer after neoadjuvant therapy.

Minerva surgery·2026
Same author

Modern treatment for achalasia: endoscopic and surgical therapies.

The British journal of surgery·2026
Same author

Prospectively screening for venous thromboembolism in patients with esophagectomy for cancer improves survival: The complexity of simplicity.

The Journal of thoracic and cardiovascular surgery·2026
Same author

Efficacy of peroral endoscopic myotomy for the treatment of functional esophagogastric junction outflow obstruction.

iGIE : innovation, investigation and insights·2026
Same author

Management of debilitating bile reflux after esophagectomy with Roux-en-Y diversion.

JTCVS techniques·2025
Same journal

Revisiting the Immunological Landscape of Locoregional Therapies for Gastrointestinal Cancers: A Shift Toward Interventional Immuno-Oncology.

Current oncology reports·2026
Same journal

Anti-PD-1 Combinations: Triplets and Beyond.

Current oncology reports·2026
Same journal

Sacituzumab Tirumotecan Across Gynecologic Malignancies: One Target, Multiple Diseases.

Current oncology reports·2026
Same journal

Clusterin in Head and Neck Squamous Cell Carcinoma: Diagnostic, Prognostic, and Therapeutic Implications.

Current oncology reports·2026
Same journal

Cardiac Risk Without a Roadmap: Lack of Evidence-Based Guidance for Cardiovascular Toxicity of T-Cell Redirecting Therapies.

Current oncology reports·2026
Same journal

Current Understanding of CHIP's Immunobiological Footprint with A Focus on Gastrointestinal Disorders: A Review of the Literature.

Current oncology reports·2026
See all related articles

Related Experiment Video

Updated: Jun 2, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
08:01

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

Malignant pleural mesothelioma.

Siva Raja1, Sudish C Murthy, David P Mason

  • 1Department of Cardiothoracic Surgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA. rajas@ccf.org

Current Oncology Reports
|May 17, 2011
PubMed
Summary
This summary is machine-generated.

Malignant pleural mesothelioma (MPM), a rare cancer linked to asbestos, presents challenges in treatment. While current therapies offer life extension, research into new treatments is ongoing for this aggressive thoracic malignancy.

More Related Videos

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
07:54

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
09:31

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model

Published on: October 2, 2015

Related Experiment Videos

Last Updated: Jun 2, 2026

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
08:01

Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines

Published on: April 21, 2022

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
07:54

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
09:31

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model

Published on: October 2, 2015

Area of Science:

  • Oncology
  • Thoracic Surgery
  • Environmental Medicine

Background:

  • Malignant pleural mesothelioma (MPM) is a rare thoracic cancer with increasing incidence.
  • Strongly associated with asbestos exposure, MPM often presents at advanced stages.
  • Past treatments for MPM included limited chemotherapy and invasive surgery.

Purpose of the Study:

  • To review the clinical presentation and diagnostic approaches for MPM.
  • To explore current treatment modalities including chemotherapy, radiation, and surgery.
  • To introduce promising new therapies under investigation for MPM.

Main Methods:

  • Literature review of clinical presentation, diagnosis, and treatment of MPM.
  • Analysis of recent studies on chemotherapy, radiation, and surgical interventions.
  • Inclusion of emerging therapeutic strategies.

Main Results:

  • MPM diagnosis is often delayed due to insidious growth.
  • Current multimodality treatments can prolong life but rarely achieve cure.
  • Aggressive surgical interventions and chemotherapy show limited efficacy.

Conclusions:

  • Despite advancements, curative treatment for MPM remains a significant challenge.
  • Multimodality strategies offer survival benefits but not a cure.
  • Ongoing research into novel therapies holds promise for improved MPM outcomes.