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Inverse analysis and robustness evaluation for biological structure behaviour in FE simulation: application to the
Cécile Conte1, Catherine Masson, Pierre-Jean Arnoux
1Laboratoire de Biomécanique Appliquée, IFSTTAR/Université de Méditerranée, Bd P. Dramard, 13 016 Marseille, France.
Summary
Understanding liver injury mechanisms is key for developing effective safety devices. This study used finite element (FE) simulation to accurately model liver behavior under impact, aiding in better injury prevention strategies.
Area of Science:
- Biomechanics
- Computational mechanics
- Medical device safety
Background:
- Preventing abdominal organ trauma requires understanding injury mechanisms and criteria.
- Finite element (FE) simulation combined with experiments offers insights into internal organ behavior during crashes.
Purpose of the Study:
- To develop a methodology for characterizing the mechanical behavior of the liver using FE simulation.
- To apply inverse analysis, optimization, and robustness studies for accurate liver modeling.
Main Methods:
- Utilized a finite element (FE) simulation approach coupled with experimental data.
- Employed an inverse analysis methodology integrating exploration process optimization and robustness study.
- Characterized the liver's hyperelastic behavior using the Mooney-Rivlin model under quasi-static compression.
Main Results:
- The developed FE model accurately fits experimental data for the whole liver structure.
- The methodology successfully obtained the mechanical behavior of the complex liver structure.
- Quantified the variability introduced by modeling parameters within a practical timeframe.
Conclusions:
- The proposed inverse analysis methodology is effective for characterizing complex biological tissues like the liver.
- FE simulation provides a valuable tool for understanding organ behavior under crash conditions.
- This approach aids in the development of more efficient safety devices for preventing abdominal trauma.
