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Updated: Jun 2, 2026

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
Published on: January 27, 2023
[Risk factors for patent ductus arteriosus in neonates]
Xiao-Yu Qu1, Xian-Feng Zhou, Yi Qu
1Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Objective:
To identify the risk factors for patent ductus arteriosus (PDA) in neonates.
Methods:
Fifty infants with PDA and 100 infants without PDA were enrolled. Chi-square test, Student's t test and the linear correlation analysis were used to study the clinical data. Logistic regression analysis was used to investigate the independent risk factors for PDA.
Results:
The prevalence of PDA was negatively correlated with the gestation age (r=-0.03, P<0.05) and birth weight (r=-0.04, P<0.05). Oxygen inhalation was a protective factor for the development of PDA. Fetal distress, meconium-stained amniotic fluid, oligohydramnios, cord entanglement, 1 minute Apgar score <8, maternal infection and hypoxic-ischemic encephalopathy were the independent risk factors for the development of PDA.
Conclusions:
The incidence of PDA can be reduced by preventing maternal infection, premature birth, low birth weight and hypoxia.
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