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Related Concept Videos

Neural Circuits01:25

Neural Circuits

Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
Spinal Cord: Information Processing01:10

Spinal Cord: Information Processing

The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Cerebrospinal Fluid01:21

Cerebrospinal Fluid

Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.
Neuronal Communication01:28

Neuronal Communication

Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
Organization of the Nervous System01:13

Organization of the Nervous System

The nervous system is one of the most complex systems in our body. It is organized into two main divisions: the central nervous system (CNS) and the peripheral nervous system (PNS).
The CNS, comprising the brain and spinal cord, houses billions of neurons. The brain is housed in the skull, while the spinal cord is linked to the brain through the foramen magnum of the occipital bone and is surrounded by the protective structure of the vertebral column. It is responsible for processing various...
Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...

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Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model
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Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model

Published on: October 18, 2015

The NeuroDevNet Neuroinformatics Core.

Elodie Portales-Casamar1, Alan Evans, Wyeth Wasserman

  • 1Centre for High-Throughput Biology, University of British Columbia, Vancouver, BC, Canada. elodie@neurodevnet.ca

Seminars in Pediatric Neurology
|May 18, 2011
PubMed
Summary
This summary is machine-generated.

Neuroinformatics is crucial for advancing brain research and treating neurodevelopmental disorders. The NeuroDevNet Neuroinformatics Core supports data management and sharing to facilitate collaborative Canadian research.

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Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
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Area of Science:

  • Neuroscience
  • Bioinformatics
  • Computational Biology

Background:

  • The field of neuroinformatics has grown significantly due to advances in brain research and computing.
  • Diverse activities include data management, standardization, and software development for analysis and visualization.

Purpose of the Study:

  • To support the Canadian NeuroDevNet initiative in studying brain development.
  • To translate neurodevelopmental research into improved diagnosis, prevention, and treatment of disorders.
  • To facilitate data management, standardization, sharing, and innovative solutions for researchers.

Main Methods:

  • Implementing data management and standardization protocols.
  • Developing sophisticated software for data analysis and visualization.
  • Fostering collaboration and knowledge sharing among researchers.

Main Results:

  • Enhanced data sharing and accessibility across the NeuroDevNet network.
  • Improved research efficiency through standardized data practices.
  • Facilitation of innovative solutions for neurodevelopmental research.

Conclusions:

  • The NeuroDevNet Neuroinformatics Core is essential for enabling collaboration and optimizing research.
  • Effective neuroinformatics infrastructure is vital for advancing the understanding and treatment of neurodevelopmental disorders.