Related Experiment Video
Updated: Jun 1, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
Refractory status epilepticus treated with vagal nerve stimulation: case report
Brent R O'Neill1, James Valeriano, Andrea Synowiec
1Department of Neurosurgery, University of Colorado, Aurora, Colorado 80045, USA. boneill35@gmail.com
Background And Importance:
Status epilepticus (SE) refractory to medical treatment has a high mortality rate and few effective treatments.
Clinical Presentation:
We describe the implantation of a vagal nerve stimulator to help terminate a case of refractory SE. A 23-year-old man was in SE for 3 weeks without being able to be weaned from intravenous anesthetic agents. After implantation of a vagal nerve stimulator, SE soon terminated, and the patient could be weaned from sedative agents and made a full recovery.
Conclusion:
Vagal nerve stimulator should be considered in cases of refractory SE.

