Related Experiment Videos
7-Acetoxy-cochinchinone I
Abstract:
The title compound {systematic name: 12-[(2E)-3,7-dimethyl-2,6-octa-dien-yl]-5,8-dihydr-oxy-2,2-dimethyl-2H,6H-pyrano[3,2-b]xanthen-6-one}, C(30)H(32)O(6), has four fused rings (A/B/C/D) and the xanthone ring system (A/B/C) is essentially planar, with dihedral angles of 1.85 (13) and 2.47 (13)°, respectively, between rings A and B, and between rings B and C. The chromene ring D is in a sofa form. The geranyl side chain is axially attached to ring C with an (-)-synclinal conformation. The 3-methyl-2-butenyl terminal of the geranyl side chain is disordered with the site-occupancy ratio of 0.513 (5):0.487 (5). The acet-oxy group is attached axially to ring A with an (+)-synclinal conformation. An intra-molecular O-H⋯O hydrogen bond involving the carbonyl and hydroxyl groups generates an S(6) ring motif. In the crystal, weak C-H⋯O and C-H⋯π inter-actions, and π-π inter-actions with centroid-centroid distances of 3.6562 (16) and 3.6565 (16) Å are observed.
Related Concept Videos
Antiasthma Drugs: Methylxanthines
Theophylline is thought to inhibit phosphodiesterase enzymes, increasing intracellular levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). This rise in cAMP and cGMP concentrations stimulates cardiac function,...
iChip
Direct-Acting Cholinergic Agonists: Therapeutic Uses
Antifungal Agents
Organic Compounds
Anthelminthic Agents