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Updated: Jun 1, 2026
11:01
Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
(E)-Methyl N'-(3-methoxy-benzyl-idene)hydrazinecarboxyl-ate
Summary
This study details the crystal structure of a compound, revealing two distinct molecular arrangements and specific bonding interactions. These findings contribute to understanding molecular packing and intermolecular forces in crystalline solids.
Area of Science:
- Crystallography
- Solid-state chemistry
- Organic chemistry
Background:
- Understanding the crystal structure of organic compounds is crucial for predicting their physical and chemical properties.
- The specific arrangement of molecules in a crystal lattice influences material behavior and reactivity.
- Intermolecular forces, such as hydrogen bonds and pi-stacking, play a significant role in crystal packing.
Purpose of the Study:
- To determine and analyze the crystal structure of the title compound, C(10)H(12)N(2)O(3).
- To investigate the molecular conformations and orientations within the crystal lattice.
- To identify and characterize the intermolecular interactions responsible for crystal stabilization.
Main Methods:
- Single-crystal X-ray diffraction was employed to obtain the diffraction data.
- The crystal structure was solved and refined using standard crystallographic software.
- Analysis of bond lengths, bond angles, and intermolecular contacts was performed.
Main Results:
- The title compound, C(10)H(12)N(2)O(3), crystallizes with two independent molecules in the asymmetric unit.
- These molecules exhibit variations in methoxy group orientation and adopt a trans configuration around the C=N bond.
- The crystal structure is characterized by chains formed via N-H⋯O and N-H⋯N hydrogen bonds, along with C-H⋯π interactions.
Conclusions:
- The crystal structure of C(10)H(12)N(2)O(3) has been elucidated, revealing molecular diversity within the asymmetric unit.
- The identified hydrogen bonding and C-H⋯π interactions are key to the observed crystal packing.
- This structural information provides a foundation for further studies on the compound's properties and potential applications.
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