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Updated: Jun 1, 2026

Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
Published on: July 28, 2022
1,5-Bis[(E)-1-(2-hydroxy-phen-yl)ethyl-idene]carbonohydrazide dimethyl sulfoxide solvate
Abstract:
The title dimethyl sulfoxide (DMSO) solvate, C(17)H(18)N(4)O(3)·C(2)H(6)OS, shows the disubstituted urea derivative to adopt an almost planar geometry (r.m.s. deviation for non-H atoms = 0.132 Å); the mol-ecule has non-crystallographic twofold mol-ecular symmetry. This conformation is stabilized by two intra-molecular O-H⋯N hydrogen bonds. The components of the crystal are connected by N-H⋯O hydrogen bonds, whereby both amine H atoms are connected to a DMSO O atom, and C-H⋯O contacts involving the DMSO H and urea carbonyl atoms, forming a supra-molecular chain along the c axis. The chains associate via C-H⋯π inter-actions.
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