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Updated: Jun 1, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
3-Acetyl-6-chloro-2-methyl-4-phenyl-quinolinium hydrogen sulfate
Abstract:
In the title salt, C(18)H(15)ClNO(+)·HSO(4) (-), the quinolinium ring system is approximately planar, with a maximum deviation of 0.028 (2) Å, and forms a dihedral angle of 78.43 (4)° with the attached phenyl ring. A pair of inter-molecular O-H⋯O hydrogen bonds links two hydrogen sulfate anions into a dimer, generating a R(2) (2)(8) ring motif. Inter-molecular N-H⋯O hydrogen bonds and C-H⋯O contacts link the ions into a three-dimensional network. The structure is further stabilized by C-H⋯π inter-actions.
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