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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
4-(4-Methoxy-phen-yl)-7,7-dimethyl-5-oxo-5,6,7,8-tetra-hydrochromene-2,5-dione
1The College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, People's Republic of China.
Abstract:
The title compound, C(18)H(20)O(4), was synthesized by the reaction of 4-methoxy-benzaldehyde, 2,2-dimethyl-1,3-dioxane-4,6-dione and 5,5-dimethyl-cyclo-hexane-1,3-dione with triethyl-benzyl-ammonium chloride in water as a green solvent. In the mol-ecule of the title compound, the six-membered pyran-one ring of the hexa-hydro-coumarin system has a screw-boat conformation while that of the dimethyl-cyclo-hexenone system has a distorted envelope conformation. The CMe(2) portion of this ring is disordered over two positions with refined occupancies of 0.721 (7) and 0.279 (7).
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