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Updated: Jun 1, 2026
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Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
Published on: November 15, 2017
2,4-Dihydr-oxy-N'-(2-hydr-oxy-4-methoxy-benzyl-idene)benzohydrazide
1Department of Chemistry and Life Sciences, Chuzhou University, Chuzhou, Anhui 239000, People's Republic of China.
Summary
This study details the crystal structure of a novel organic compound, C(15)H(14)N(2)O(5). The research highlights specific molecular configurations and intermolecular interactions, revealing a layered crystal arrangement.
Area of Science:
- Crystallography
- Organic Chemistry
- Materials Science
Background:
- Understanding molecular structure and intermolecular forces is crucial in materials science.
- Crystal engineering aims to design materials with specific properties based on predictable intermolecular interactions.
- The compound C(15)H(14)N(2)O(5) presents an interesting scaffold for investigating such interactions.
Purpose of the Study:
- To elucidate the detailed crystal structure of the organic compound C(15)H(14)N(2)O(5).
- To analyze the molecular conformation, including dihedral angles and stereochemistry around the C=N bond.
- To identify and characterize intra- and intermolecular hydrogen bonding networks and their role in crystal packing.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the three-dimensional molecular and crystal structure.
- Analysis of bond lengths, bond angles, and dihedral angles provided insights into the molecular geometry.
- Hydrogen bond analysis was performed to identify and quantify intra- and intermolecular interactions.
Main Results:
- The crystal structure of C(15)H(14)N(2)O(5) was successfully determined, revealing a dihedral angle of 4.3(3)° between the two benzene rings.
- The molecule adopts an E configuration about the C=N double bond.
- Intramolecular hydrogen bonds (O-H⋯N and N-H⋯O) were observed within the molecule, and intermolecular hydrogen bonds (N-H⋯O and O-H⋯O) mediate the formation of layered structures parallel to the ac plane.
Conclusions:
- The study provides a comprehensive structural characterization of C(15)H(14)N(2)O(5).
- The identified hydrogen bonding patterns are key to the observed layered crystal architecture.
- These findings contribute to the understanding of structure-property relationships in organic crystalline materials.
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