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Published on: October 30, 2018
Isopropyl 3-(3,4-dihydroxy-phen-yl)-2-hydroxy-propanoate
Summary
This study characterizes a novel compound, a derivative of β-(3,4-dihydroxy-phenyl)-α-hydroxy acid. Its crystal structure reveals stabilization through intermolecular hydrogen bonds.
Area of Science:
- Organic Chemistry
- Crystallography
Background:
- The study focuses on a specific organic compound with the molecular formula C(12)H(16)O(5).
- This compound is identified as a derivative of β-(3,4-dihydroxy-phenyl)-α-hydroxy acid.
Purpose of the Study:
- To elucidate the chemical structure and properties of the title compound.
- To investigate the intermolecular interactions governing its crystal packing.
Main Methods:
- Chemical synthesis and characterization of the compound C(12)H(16)O(5).
- X-ray crystallography to determine the crystal structure.
- Analysis of hydrogen bonding networks within the crystal lattice.
Main Results:
- The compound was identified as a derivative of β-(3,4-dihydroxy-phenyl)-α-hydroxy acid.
- Crystal structure analysis revealed the presence of inter-molecular O-H⋯O hydrogen bonds.
- These hydrogen bonds play a crucial role in stabilizing the crystal packing.
Conclusions:
- The title compound possesses a defined molecular structure and packing arrangement.
- Intermolecular hydrogen bonds are key stabilizing forces in the crystal structure of this dihydroxy-phenyl derivative.
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02:23Structure and Nomenclature of Alcohols and Phenols
Overview
Alcohols are one of the most important functional groups in organic chemistry. The name of alcohol comes from the hydrocarbon from which it is derived. Alcohols are organic molecules containing the functional hydroxyl or –OH group directly bonded to carbon. Phenols have an OH group directly attached to a benzene ring. While alcohols are colorless, phenol is a white crystalline compound with a characteristic "hospital smell" odor.
As with other organic compounds, alcohols and phenols...
Alcohols are one of the most important functional groups in organic chemistry. The name of alcohol comes from the hydrocarbon from which it is derived. Alcohols are organic molecules containing the functional hydroxyl or –OH group directly bonded to carbon. Phenols have an OH group directly attached to a benzene ring. While alcohols are colorless, phenol is a white crystalline compound with a characteristic "hospital smell" odor.
As with other organic compounds, alcohols and phenols...
01:16IUPAC Nomenclature of Aldehydes
Aldehydes are named based on the systematic nomenclature rules set by the IUPAC. For acyclic aldehydes, the longest carbon chain containing the aldehydic (–CHO) group is considered the parent chain. The aldehyde is named by replacing the last letter “e” in the hydrocarbon name with “al”. For instance, a simple, seven-carbon-membered acyclic aldehyde is called heptanal, derived from heptane. The carbon chain is numbered starting from the aldehydic carbon, although the aldehydic carbon’s locant...
02:32Physical Properties of Alcohols and Phenols
Alcohols are organic compounds in which a hydroxy group is attached to a saturated carbon. Phenols are a class of alcohols containing a hydroxy group attached to an aromatic ring. The physical properties of the alcohols and phenols are influenced by hydrogen bonding due to the oxygen–hydrogen dipole in the hydroxy functional group and dispersion forces between alkyl or aryl regions of alcohol and phenol molecules.
Alcohols possess a higher boiling point than aliphatic hydrocarbons of similar...
Alcohols possess a higher boiling point than aliphatic hydrocarbons of similar...
01:57Preparation of Diols and Pinacol Rearrangement
Compounds bearing two hydroxyl groups are known as diols. When the hydroxyl groups are located on adjacent carbon atoms, the diols are called vicinal diols or glycols. Under acidic conditions, vicinal diols undergo a specific reaction called pinacol rearrangement.
The reaction begins with transferring a proton from the acid catalyst to one of the hydroxyl groups, producing an oxonium ion.
The reaction begins with transferring a proton from the acid catalyst to one of the hydroxyl groups, producing an oxonium ion.
02:31Protection of Alcohols
This lesson delves into the concept of protection and deprotection of a functional group fundamental to synthetic organic chemistry. These phenomena are explained in the context of aliphatic and aromatic alcohols.
Protection
It defines a protecting group as the masking agent to make the more reactive species inert to a given set of conditions. This concept is depicted via the illustration of liquid flow through different outlets in an assembly of pipes. The analogy helps to understand the role...
Protection
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