Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nomenclature of Aryl and Heterocyclic Amines01:10

Nomenclature of Aryl and Heterocyclic Amines

The simplest aromatic amine is phenylamine, which contains an –NH2 functionality directly attached to an aromatic ring. The name aniline is designated for this skeleton. As shown in Figure 1, the common names of the functionalized anilines involve prefixes ortho-, meta-, and para- to indicate the substitution position. Different functionalized aniline derivatives also have notable trivial names.
Aryldiazonium Salts to Azo Dyes: Diazo Coupling01:11

Aryldiazonium Salts to Azo Dyes: Diazo Coupling

The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the para position.
Cholinergic Antagonists: Chemistry and Structure-Activity Relationship01:29

Cholinergic Antagonists: Chemistry and Structure-Activity Relationship

Cholinergic antagonists bind to cholinergic receptors and limit the effects of acetylcholine and other cholinergic agonists. Based on the specific cholinergic receptor affinity, these antagonists are classified as muscarinic or nicotinic. Anticholinergics interrupt parasympathetic innervations while sympathetic innervations remain uninterrupted. Muscarinic antagonists are also called 'muscarinic antagonists', 'antimuscarinics', or 'parasympatholytics'. Nicotinic antagonists are called...
Cholinergic Antagonists: Pharmacokinetics01:24

Cholinergic Antagonists: Pharmacokinetics

Cholinergic antagonists—such as antimuscarinics—are available in oral, topical, ocular, parenteral, and inhalational formulations. Most antimuscarinics are oral formulations,  while scopolamine is available as a topical patch, and ipratropium and tiotropium are available as inhalation aerosols or powders. Atropine, tropicamide, and cyclopentolate are topically instilled in the eye. Most antimuscarinics are lipid-soluble and readily absorbed from the gastrointestinal tract and the conjunctiva.
Physical Properties of Amines01:26

Physical Properties of Amines

Amines with low molecular weight are usually gaseous at room temperature, while those with high molecular weight are liquid or solids in nature. Usually, low molecular weight amines have a rotten fish-like smell. Diamines typically have a pungent smell. For instance, cadaverine and putrescine, depicted in Figure 1, are two molecules responsible for decaying tissue.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recent Progress on Graphene Flexible Photodetectors.

Materials (Basel, Switzerland)·2022
Same author

Lotus Seedpod-Inspired Crosslinking-Assembled Hydrogels Based on Gold Nanoclusters for Synergistic Osteosarcoma Multimode Imaging and Therapy.

ACS applied materials & interfaces·2022
Same author

Prognostic Factors for Excellent Response to Initial Therapy in Patients With Papillary Thyroid Cancer From a Prospective Multicenter Study.

Frontiers in oncology·2022
Same author

Electrode Interface Engineering in Lithium-Sulfur Batteries Enabled by a Trifluoroacetamide-Based Electrolyte.

ACS applied materials & interfaces·2022
Same author

Inter- and intra-chromosomal modulators of the APOE ɛ2 and ɛ4 effects on the Alzheimer's disease risk.

GeroScience·2022
Same author

Influence of improved behavioral inhibition on decreased cue-induced craving in heroin use disorder: A preliminary intermittent theta burst stimulation study.

Journal of psychiatric research·2022

Related Experiment Video

Updated: Jun 1, 2026

Optimized Griess Reaction for UV-Vis and Naked-eye Determination of Anti-malarial Primaquine
08:31

Optimized Griess Reaction for UV-Vis and Naked-eye Determination of Anti-malarial Primaquine

Published on: October 11, 2019

1-(2-Methoxy-anilino)anthraquinone.

Lihua Lu, Liang He

    Acta Crystallographica. Section E, Structure Reports Online
    |May 18, 2011
    PubMed
    Summary

    This study details the molecular structure of a novel organic compound, C(21)H(15)NO(3). Its conformation is influenced by a significant dihedral angle and stabilized by an intramolecular hydrogen bond.

    Area of Science:

    • Organic Chemistry
    • Crystallography
    • Molecular Structure

    Background:

    • Understanding molecular conformation is crucial in organic chemistry.
    • Intramolecular interactions dictate the three-dimensional shape of molecules.
    • Aromatic systems and functional groups play key roles in molecular geometry.

    Purpose of the Study:

    • To elucidate the precise molecular structure of the title compound, C(21)H(15)NO(3).
    • To investigate the conformational preferences and stabilizing interactions within the molecule.

    Main Methods:

    • Single-crystal X-ray diffraction was employed to determine the molecular structure.
    • Analysis of bond lengths, bond angles, and dihedral angles was performed.
    • Identification of intramolecular hydrogen bonding was conducted.

    More Related Videos

    Facile Preparation of 4-Substituted Quinazoline Derivatives
    11:51

    Facile Preparation of 4-Substituted Quinazoline Derivatives

    Published on: February 15, 2016

    Related Experiment Videos

    Last Updated: Jun 1, 2026

    Optimized Griess Reaction for UV-Vis and Naked-eye Determination of Anti-malarial Primaquine
    08:31

    Optimized Griess Reaction for UV-Vis and Naked-eye Determination of Anti-malarial Primaquine

    Published on: October 11, 2019

    Facile Preparation of 4-Substituted Quinazoline Derivatives
    11:51

    Facile Preparation of 4-Substituted Quinazoline Derivatives

    Published on: February 15, 2016

    Main Results:

    • The dihedral angle between the aromatic ring systems was determined to be 71.50(3)°.
    • The methoxy group was found to be coplanar with its connected benzene ring (torsion angle 6.37(17)°).
    • An intramolecular N-H⋯O hydrogen bond was identified, forming an S(6) ring.

    Conclusions:

    • The crystal structure reveals a specific, non-planar conformation for C(21)H(15)NO(3).
    • The observed conformation is significantly stabilized by a strong intramolecular hydrogen bond.
    • This structural insight contributes to the understanding of molecular design and interactions in organic compounds.