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Updated: Jun 1, 2026
11:51
Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
2,4-Dichloro-quinoline
Summary
This study reveals the crystal structure of a dichloroquinoline compound, C(9)H(5)Cl(2)N. Two independent molecules exhibit planar quinoline rings, arranged in an alternating AABB pattern stabilized by weak intermolecular interactions.
Area of Science:
- Crystallography
- Organic Chemistry
- Materials Science
Background:
- Understanding the solid-state structure of organic compounds is crucial for predicting their physical and chemical properties.
- Dichloroquinoline derivatives are of interest due to their potential applications in various fields.
Purpose of the Study:
- To determine the crystal structure of the title compound, C(9)H(5)Cl(2)N.
- To analyze the molecular arrangement and intermolecular interactions within the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to elucidate the three-dimensional structure.
- Crystallographic data were collected and analyzed to determine bond lengths, angles, and molecular packing.
Main Results:
- The asymmetric unit contains two crystallographically independent molecules with planar quinoline ring systems.
- These molecules adopt an alternating face-to-face arrangement (AABB) along the c-axis.
- Crystal packing is stabilized by weak C-H⋯Cl and C-H⋯N interactions.
Conclusions:
- The study provides detailed insights into the solid-state structure of this dichloroquinoline compound.
- The observed molecular arrangement and interactions offer a basis for understanding its material properties.
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