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Updated: Jun 1, 2026

A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Published on: August 16, 2018
4-(3,4-Dimethyl-5-phenyl-1,3-oxazolidin-2-yl)-2-methoxy-phenol
Abstract:
In the title compound, C(18)H(21)NO(3), the oxazolidine ring adopts an envelope conformation with the N atom at the flap position. The two benzene rings make dihedral angles of 74.27 (14) and 73.26 (15)° with the mean plane through the oxazolidine ring. In the crystal structure, O-H⋯O and C-H⋯O hydrogen bonds connect adjacent mol-ecules into chains along [010] incorporating R(2) (2)(8) loops and further stabilization is provided by weak inter-molecular C-H⋯π inter-actions.
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