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Related Concept Videos

Oxidation of Phenols to Quinones01:17

Oxidation of Phenols to Quinones

In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox property is crucial in...
Structure and Nomenclature of Alcohols and Phenols02:23

Structure and Nomenclature of Alcohols and Phenols

Overview
Alcohols are one of the most important functional groups in organic chemistry. The name of alcohol comes from the hydrocarbon from which it is derived. Alcohols are organic molecules containing the functional hydroxyl or –OH group directly bonded to carbon. Phenols have an OH group directly attached to a benzene ring. While alcohols are colorless, phenol is a white crystalline compound with a characteristic "hospital smell" odor.
As with other organic compounds, alcohols and phenols...
Radical Chain-Growth Polymerization: Overview01:10

Radical Chain-Growth Polymerization: Overview

Chain-growth or addition polymerization is successive addition reactions of monomers with a polymer chain. In radical chain-growth polymerization, the reaction proceeds via a free-radical intermediate. The free radical is formed from radical initiators, which spontaneously generate free radicals by homolytic fission. Organic peroxides (such as dibenzoyl peroxide, as shown in Figure 1) or azo compounds are popular radical initiators. A low concentration ratio of radical initiator to monomer is...
Nomenclature of Aromatic Compounds with Multiple Substituents01:11

Nomenclature of Aromatic Compounds with Multiple Substituents

When more than one substituent is present on the benzene ring, the IUPAC nomenclature depends on the number of substituents present.
For disubstituted benzene derivatives, with two groups attached to the benzene ring, three constitutional isomers are possible. For example, consider dimethyl benzene, often called xylene, where the second methyl group can be substituted at the second, third, or fourth carbon. The relative position of the substituents is represented by prefixes ortho, meta, or...
NMR Spectroscopy of Benzene Derivatives01:37

NMR Spectroscopy of Benzene Derivatives

Simple unsubstituted benzene has six aromatic protons, all chemically equivalent. Therefore, benzene exhibits only a singlet peak at δ 7.3 ppm in the 1H NMR spectrum. The observed shift is far downfield because the aromatic ring current strongly deshields the protons. Any substitution on the benzene ring makes the aromatic protons nonequivalent, and the protons split each other. The peak is, therefore, no longer a singlet and the splitting pattern and their associated coupling constants depend...

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Related Experiment Video

Updated: Jun 1, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
11:51

Facile Preparation of 4-Substituted Quinazoline Derivatives

Published on: February 15, 2016

2,3-Bis(4-ethoxy-phen-yl)quinoxaline.

Ping-Ping Ye1, Cai-Li Zhang, Zhi-Qiang Du

  • 1Department of Chemistry, Zhejiang University, Hangzhou 310027, People's Republic of China.

Acta Crystallographica. Section E, Structure Reports Online
|May 18, 2011
PubMed
Summary

Researchers synthesized a novel organic compound, C(24)H(22)N(2)O(2), using a condensation reaction. Structural analysis revealed a twisted quinoxaline core and crystal packing influenced by weak C-H⋯π interactions.

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Green Synthesis of Quinoline-Based Ionic Liquid
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Facile Preparation of 4-Substituted Quinazoline Derivatives
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Facile Preparation of 4-Substituted Quinazoline Derivatives

Published on: February 15, 2016

Green Synthesis of Quinoline-Based Ionic Liquid
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Green Synthesis of Quinoline-Based Ionic Liquid

Published on: September 27, 2024

Area of Science:

  • Organic Chemistry
  • Crystallography
  • Materials Science

Background:

  • Quinoxaline derivatives are important heterocyclic compounds with diverse applications.
  • Understanding the structure-property relationships of novel organic molecules is crucial for developing new materials.

Purpose of the Study:

  • To synthesize and characterize a new organic compound with the molecular formula C(24)H(22)N(2)O(2).
  • To elucidate the crystal structure and intermolecular interactions of the synthesized compound.

Main Methods:

  • Condensation reaction between 1,2-bis-(4-ethoxy-phenyl)ethane-1,2-dione and 1,2-diamino-benzene.
  • Single-crystal X-ray diffraction analysis to determine the molecular and crystal structure.

Main Results:

  • The compound was successfully synthesized and its structure confirmed.
  • The crystal structure revealed a twisted conformation of the quinoxaline ring relative to the ethoxy-phenyl groups, with dihedral angles of approximately 39.95 degrees.
  • Crystal packing is primarily governed by weak C-H⋯π interactions, with no classical hydrogen bonds or π-π stacking observed.

Conclusions:

  • The study successfully synthesized and characterized a novel organic compound.
  • The detailed structural analysis provides insights into the conformational preferences and intermolecular forces governing the crystal packing of this molecule.
  • The findings contribute to the understanding of quinoxaline-based organic materials.