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Updated: Jun 1, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
2,3-Bis(4-ethoxy-phen-yl)quinoxaline
Ping-Ping Ye1, Cai-Li Zhang, Zhi-Qiang Du
1Department of Chemistry, Zhejiang University, Hangzhou 310027, People's Republic of China.
Abstract:
The title compound, C(24)H(22)N(2)O(2), was prepared by condensation of 1,2-bis-(4-ethoxy-phen-yl)ethane-1,2-dione and 1,2-diamino-benzene. The asymmetric unit contains one half-mol-ecule, close to a twofold axis. The plane of the quinoxaline ring is twisted with respect to the planes of the two ethoxy-phenyl ring systems, exhibiting dihedral angles of 39.95 (9)°. The crystal packing is dominated by weak C-H⋯π inter-actions. No classical hydrogen bonds or stacking inter-actions are observed.
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