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Updated: Jun 1, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
(Z)-Ethyl 2-hydroxy-imino-2-(4-nitro-benz-yl)ethanoate
Abstract:
The title mol-ecule, C(11)H(10)N(2)O(6), has a Z conformation about the C=N bond of the oxime unit. There are significant twists from planarity throughout the mol-ecule, the most significant being between the hydroxy-imino and ester groups which are effectively orthogonal with an N-C-C-O(carbon-yl) torsion angle of 91.4 (2)°. The crystal packing features oxime-benzoyl O-H⋯O contacts that lead to chains along [010] and C-H⋯O interactions also occur.
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