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Updated: Jun 1, 2026

Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
Published on: July 28, 2022
1,12-Bis(2-carboxy-phen-yl)-5,8-dioxa-2,11-diaza-dodecane-2,11-diium dichloride methanol solvate
Abstract:
In the title salt hydrate, C(22)H(30)N(2)O(6) (2+)·2Cl(-)·CH(4)O, the dication adopts a U-shaped conformation whereby the benzene rings are splayed out from the chain linking them. All components of the asymmetric unit are linked into a cohesive entity by a combination of O-H⋯Cl(-), N(+)-H⋯Cl(-) and N(+)-H⋯O charge-assisted hydrogen-bonding inter-actions. The assemblies thus formed are linked into supra-molecular helical chains along [010] via C-H⋯O contacts. The resulting chains are, in turn, consolidated into the three-dimensional crystal structure by C-H⋯π contacts.
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