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Updated: Jun 1, 2026

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
2-Ferrocenyl-N-(6-methyl-2-pyrid-yl)benzamide
Abstract:
The title compound, [Fe(C(5)H(5))(C(18)H(15)N(2)O)], a product of the reaction of 2-ferrocenylbenzoic acid and 2-amino-6-methyl-pyridine, crystallizes with two dissimilar mol-ecules in the asymmetric unit. In one mol-ecule, the picoline amide group is directed away from the 2-ferrocenylbenzene moiety (anti) whereas in the other, these are proximate (syn). In the crystal structure, mol-ecules aggregate into dimers via cyclic, asymmetric N-H⋯N inter-actions with graph set R(2) (2)(8), and are further augmented via intra-molecular C-H⋯O=C and inter-dimer C-H⋯π(arene) inter-actions. Dimers are linked into chains along the [102] direction via weak C-H⋯O hydrogen bonds.
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