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Updated: Jun 1, 2026
![Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F2755.jpg&w=3840&q=50)
Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate ([18F]SFB)
Published on: June 28, 2011
N-(2-Methyl-phen-yl)succinamic acid
Abstract:
In the crystal structure of the title compound, C(11)H(13)NO(3), the conformations of the N-H and C=O bonds in the amide segment are anti to each other and that of the amide H atom is syn to the ortho-methyl group in the benzene ring. In the crystal, O-H⋯O interactions lead to carboxylic acid inversion dimers and inter-molecular N-H⋯O hydrogen bonds link the mol-ecules into infinite chains. In addition, the crystal structure exhibits inter-molecular C-H⋯π inter-actions between one of the methyl H atoms and the benzene ring of neighbouring mol-ecules.
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