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Updated: Jun 1, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
Dimethyl 4-(3-hydroxy-phen-yl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate
Abstract:
The 1,4-dihydro-pyridine ring in the title compound, C(17)H(19)NO(5), has a flattened-boat conformation, and the benzene ring is almost orthogonal to it [dihedral angle = 82.98 (12)°]. The hydr-oxy group is disordered over two positions in a 0.780 (4):0.220 (4) ratio. In the crystal, hydrogen-bonding inter-actions of the type N(a)-H⋯O(c) and O(h)-H⋯O(c) (a = amine, c = carbonyl and h = hydr-oxy) link the mol-ecules into a three-dimensional network.
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