3-Bromo-N'-(3,5-dichloro-2-hydroxy-benzyl-idene)benzohydrazide

Area of Science:

• Organic Chemistry
• Crystallography
• Supramolecular Chemistry

Background:

• Benzaldehyde and benzohydrazide derivatives are important scaffolds in medicinal chemistry.
• Understanding the structural and bonding properties of novel organic compounds is crucial for materials science and drug discovery.

Purpose of the Study:

• To synthesize and characterize a new organic compound with the formula C(14)H(9)BrCl(2)N(2)O(2).
• To investigate the crystal structure, including dihedral angles and hydrogen bonding patterns, of the synthesized compound.

Main Methods:

• Chemical synthesis involving the reaction of 3,5-dichloro-2-hydroxy-benzaldehyde with 3-bromo-benzohydrazide in methanol.
• X-ray crystallography to determine the molecular structure and intermolecular interactions.

Main Results:

• The title compound, C(14)H(9)BrCl(2)N(2)O(2), was successfully synthesized.
• X-ray diffraction analysis revealed a dihedral angle of 13.0(2)° between the two benzene rings.
• An intramolecular O-H⋯N hydrogen bond and intermolecular N-H⋯O hydrogen bonds forming chains along the c axis were identified.

Conclusions:

• The study reports the successful synthesis and detailed structural characterization of a novel organic compound.
• The identified hydrogen bonding network provides insights into the supramolecular assembly of the compound in the solid state.
• The findings contribute to the understanding of structure-property relationships in halogenated aromatic compounds.