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Updated: Jun 1, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
Methyl 4-(3-chloro-prop-oxy)-3-methoxy-benzoate
Min Zhang1, Ran-Zhe Lu, Lu-Na Han
1College of Science, Nanjing University of Technology, Xinmofan Road No.5 Nanjing, Nanjing 210009, People's Republic of China.
The crystal structure of a novel compound, C(12)H(15)ClO(4), was determined. Molecules in this compound are interconnected through specific C-H⋯O interactions, revealing key structural features.
Area of Science:
- Crystallography
- Chemical Physics
- Organic Chemistry
Background:
- Understanding molecular interactions is crucial for predicting material properties.
- C-H⋯O interactions are a significant type of non-covalent bonding in organic crystals.
Purpose of the Study:
- To elucidate the crystal structure of the compound C(12)H(15)ClO(4).
- To identify and characterize the intermolecular interactions present in the crystal lattice.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of the crystal structure to identify and quantify C-H⋯O interactions.
Main Results:
- The crystal structure of C(12)H(15)ClO(4) was successfully determined.
- Specific C-H⋯O interactions were identified as the primary mode of molecular assembly in the crystal.
Conclusions:
- The compound C(12)H(15)ClO(4) exhibits a crystal structure stabilized by C-H⋯O interactions.
- These findings contribute to the understanding of intermolecular forces in organic solids.
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