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Updated: Jun 1, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
(E)-N-[2-(3,5-Di-tert-butyl-2-hydroxy-benzyl-ideneamino)cyclo-hexyl]-4-methyl-benzene-sulfonamide
Jincai Wu1, Lei Wang, Xiaobo Pan
1College of Chemistry and Chemical Engineering, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, People's Republic of China.
Abstract:
In the crystal structure of the title compound, C(28)H(40)N(2)O(3)S, there are two mol-ecules per asymmetric unit; in each of these mol-ecules, the cyclo-hexyl rings adopt chair conformations. The dihedral angles between the benzene rings are 16.89 (9) and 34.11 (9)°. Each mol-ecule contains an intra-molecular O-H⋯N hydrogen bond, and inter-molecular N-H⋯O hydrogen bonds are also present. In both mol-ecules, the methyl groups of one tert-butyl group are disordered over two positions; the site-occupancy factors in both cases are ca 0.6 and 0.4.
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