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Updated: Jun 1, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
3-(1H-Benzimidazol-2-yl)-2-chloro-8-methyl-quinoline
Abstract:
Two independent mol-ecules of the title compound, C(17)H(12)ClN(3), are present in the structure. The angle between the planes defined by the atoms of the benzimidazole unit and the quinoline unit are 45.2 (3) and 44.0 (3)°, indicating an essentially identical conformation for both mol-ecules. Each of the independent mol-ecules is linked with a symmetry equivalent by an inter-molecular N-H⋯N hydrogen bond involving the two benzimidazole N atoms, to form chains in the crystallographic c direction.
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