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Updated: Jun 1, 2026
14:11
Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
2-(2,6-Dichloro-benz-yl)pyrrolidine-1,3-dione.
Summary
This study details the molecular structure of a novel compound, C(11)H(9)Cl(2)NO(2). The research reveals a significant dihedral angle between its aromatic and pyrrolidinedione rings, crucial for understanding its chemical properties.
Area of Science:
- Crystallography and Molecular Structure
- Organic Chemistry
Background:
- Understanding the three-dimensional arrangement of atoms in organic molecules is fundamental to predicting their chemical behavior and potential applications.
- The pyrrolidinedione moiety is present in various biologically active compounds, making its structural characterization important.
Purpose of the Study:
- To elucidate the precise crystal structure and molecular geometry of the title compound, C(11)H(9)Cl(2)NO(2).
- To quantify the spatial relationship between the aromatic and pyrrolidinedione rings within the molecule.
Main Methods:
- Single-crystal X-ray diffraction analysis was employed to determine the molecular structure.
- The dihedral angle between the mean planes of the aromatic ring and the pyrrolidinedione ring was precisely calculated.
Main Results:
- The crystal structure of C(11)H(9)Cl(2)NO(2) was successfully determined.
- A notable dihedral angle of 79.98(9)° was measured between the aromatic and pyrrolidinedione ring systems.
Conclusions:
- The determined dihedral angle provides critical insights into the molecule's conformation.
- This structural information is vital for further research into the compound's reactivity and potential applications in medicinal chemistry or materials science.
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