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Updated: Jun 1, 2026

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis
Published on: November 17, 2011
3β,12β,14α-Trihydroxy-pregnan-20-one
1Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People's Republic of China.
Abstract:
The title compound, C(21)H(34)O(4), is a steriod of the pregnane family prepared by the sequential oxidation and reduction of 3β,12β-diacet-oxy-20-ethyl-enedioxy-pregnan-14-ene. The con-formations of the six-membered rings are close to chair forms, while the five-membered ring adopts an envelope conformation. All the rings are trans-fused and an intra-molecular O-H⋯O hydrogen bond occurs. In the crystal structure, inter-molecular O-H⋯O hydrogen bonds link the mol-ecules into a two-dimensional network.
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