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Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
Rotavirus Vaccine Coverage in a Birth Cohort - China, 2019-2023.
Yingxia Li1,2,3, Yifan Song2,3, Zhaonan Zhang2,3
1Changsha Center for Disease Control and Prevention (Changsha Health Inspection Institute), Changsha City, Hunan Province, China.
China CDC Weekly
|June 5, 2026
Summary
Rotavirus vaccination coverage in China remains low, with incomplete series completion, despite an upward trend. Strategies to improve follow-up for missed doses and clinic accessibility are recommended for better public health outcomes.
Area of Science:
- Pediatric infectious diseases
- Vaccinology
- Public health surveillance
Background:
- Rotavirus is a leading cause of severe gastroenteritis and mortality in children under five globally.
- Vaccination is a critical preventive measure against rotavirus infection.
- Nationwide data on rotavirus vaccine coverage in China were previously unavailable.
Purpose of the Study:
- To assess national rotavirus vaccine coverage trends among children in China.
- To identify factors associated with suboptimal vaccine uptake and series completion.
- To provide evidence-based recommendations for improving rotavirus immunization programs.
Main Methods:
- Analysis of data from the National Immunization Program Information System in China.
- Inclusion of children born between 2019 and 2023.
- Examination of vaccine coverage rates and series completion.
- Exploration of disparities related to socioeconomic factors and clinic density for non-program vaccines.
Main Results:
- Rotavirus vaccine coverage shows an upward trend but remains low among the target population.
- Suboptimal completion of the rotavirus vaccine series was observed.
- Disparities in coverage were noted for non-National Immunization Program (non-program) vaccines based on socioeconomic region and clinic density.
Conclusions:
- Despite progress, rotavirus vaccine uptake in China requires significant improvement.
- Strategies focusing on follow-up for missed doses, enhanced clinic accessibility, and alternative financing models are crucial.
- Addressing regional and socioeconomic disparities is essential for equitable vaccine access and improved public health outcomes.
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