2-Chloro-N-(3-chloro-phen-yl)acetamide.

Area of Science:

• Organic Chemistry
• Crystallography

Background:

• Understanding the spatial arrangement of atoms and bonds in organic molecules is crucial for predicting chemical reactivity and physical properties.
• Aromatic compounds with halogen and nitro substituents exhibit diverse structural motifs and intermolecular interactions.

Purpose of the Study:

• To elucidate the crystal structure and intermolecular interactions of a specific dichloro-nitro aromatic compound, C(8)H(7)Cl(2)NO.
• To analyze the conformational preferences and hydrogen bonding patterns within the crystal lattice.

Main Methods:

• Single-crystal X-ray diffraction was employed to determine the three-dimensional structure of the compound.
• Analysis of bond lengths, bond angles, and intermolecular contacts was performed.

Main Results:

• The N-H bond was found to be anti to the meta-chloro substituent on the aromatic ring in both independent molecules.
• The carbonyl (C=O) bond exhibited an anti-orientation relative to the N-H bond and the methylene (CH2) hydrogens.
• Intermolecular N-H⋯O hydrogen bonds were identified, leading to the formation of supra-molecular chains.

Conclusions:

• The crystal structure confirms specific conformational preferences dictated by substituent arrangements in the dichloro-nitro aromatic compound.
• The observed hydrogen bonding network plays a significant role in the supra-molecular assembly and stability of the crystal.