Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[ACE inhibitors and heart failure].

F Franchi1, G M Puddu

  • 1Università degli Studi di Bologna, Istituto di Patologia Speciale Medica e Metodologia Clinica.

La Clinica Terapeutica
|March 31, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

RoboticAssisted (RATS) versus Video-Assisted (VATS) lobectomy: A monocentric prospective randomized trial.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2023
Same author

Prognostic bioindicators in severe COVID-19 patients.

Cytokine·2021
Same author

A Metabolic Intravascular Platform to Study FDG Uptake in Vascular Injury.

Cardiovascular engineering and technology·2020
Same author

Prematurity, ventricular septal defect and dysmorphisms are independent predictors of pathogenic copy number variants: a retrospective study on array-CGH results and phenotypical features of 293 children with neurodevelopmental disorders and/or multiple congenital anomalies.

Italian journal of pediatrics·2018
Same author

Diagnostic application of a capture based NGS test for the concurrent detection of variants in sequence and copy number as well as LOH.

Clinical genetics·2017
Same author

von Willebrand disease type 1 mutation p.Arg1379Cys and the variant p.Ala1377Val synergistically determine a 2M phenotype in four Italian patients.

Haemophilia : the official journal of the World Federation of Hemophilia·2016

Angiotensin-converting enzyme (ACE) inhibitors significantly improve survival in heart failure patients by dilating blood vessels and modulating harmful neuro-endocrine responses. While several ACE inhibitors exist, individual patient needs should guide drug selection for optimal outcomes.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Heart failure is a significant clinical condition associated with increased morbidity and mortality.
  • Neuro-endocrine activation, including the renin-angiotensin-aldosterone system, plays a crucial role in the pathophysiology of heart failure.

Purpose of the Study:

  • To review the therapeutic effectiveness of ACE inhibitors in heart failure.
  • To discuss the mechanisms of action and available agents in Italy.

Main Methods:

  • Review of existing literature on ACE inhibitors in heart failure treatment.
  • Analysis of pharmacological characteristics, effectiveness, and tolerability of available ACE inhibitors.

Main Results:

  • ACE inhibitors demonstrate considerable therapeutic effectiveness and prolong survival in heart failure patients.

Related Experiment Videos

  • Benefits are attributed to vasodilation and modulation of neuro-endocrine responses like angiotensin-aldosterone production.
  • Four ACE inhibitors (captopril, enalapril, lisinopril, quinapril) are available in Italy with similar efficacy and tolerability.

    • Conclusions:

    • ACE inhibitors are vital in managing heart failure.
    • The choice of a specific ACE inhibitor should be individualized based on patient-specific factors and pharmacological properties.