Related Experiment Video
Updated: Jun 1, 2026
05:52
Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Challenges in conducting psychiatry studies in India
Saifuddin Kharawala1, Jeroze Dalal
1Clinical Research Consultant, Consultant Psychiatrist, GlaxoSmithKline Pharmaceuticals India Ltd., Mumbai, Maharashtra, India.
Perspectives in Clinical Research
|May 18, 2011
Summary
Conducting psychiatry studies in India presents unique ethical and logistical challenges, including informed consent and recruitment difficulties. Addressing these requires specialized training and careful consideration of the Indian context for successful trials.
Area of Science:
- Psychiatry
- Clinical Trials
- Medical Research
Background:
- India is a significant location for conducting psychiatric studies.
- These studies face unique challenges within the Indian context.
Purpose of the Study:
- To outline the complexities and challenges encountered in psychiatric research in India.
- To provide recommendations for the successful execution of these studies.
Main Methods:
- The study identifies common ethical issues such as informed consent validity and placebo use.
- It highlights recruitment challenges including investigator training and patient eligibility.
- It discusses the high placebo response rate and its impact on trial outcomes.
Main Results:
- Ethical considerations include managing illness worsening and ensuring valid informed consent.
- Investigator training in Good Clinical Practice (GCP) is limited, impacting site selection.
- Patient recruitment is hindered by strict criteria and caregiver availability.
- High placebo response rates contribute to trial failures.
- Adaptation of rating scales and rater training is crucial for accurate assessments.
Conclusions:
- Psychiatry studies in India require specialized training and expertise.
- Addressing ethical dilemmas and logistical hurdles is key to successful research.
- Adapting methodologies to the local context is essential for valid and reliable results.
Related Concept Videos
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
01:30Psychosurgery
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
01:29Psychological and Sociocultural Causes of Schizophrenia
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
01:16Clinical Trials
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
01:24Treatment Strategies for Psychological Disorders
Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
01:15Bioavailability Study Design: Healthy Subjects Versus Patients
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...