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Updated: Jun 1, 2026

Characterizing Mutational Load and Clonal Composition of Human Blood
Published on: July 11, 2019
clonality V.0.4: a randomization-based program to test for heterozygosity-genet size relationships in clonal
Franck Prugnolle1, Marc Choisy, Thierry DE Meeûs
1Laboratoire Génétique et Evolution des Maladies Infectieuses, UMR 2724 CNRS-IRD-UMI, Centre IRD, 911 Av. Agropolis, BP 64501, 34394 Montpellier Cedex 5, France.
Abstract:
clonality V.0.4 is a program for testing heterozygosity-genet size relationships in clonal organisms using a randomization procedure. The software has been developed under the Borland Delphi developing environment and a Windows-executable version is freely downloadable from http://gemi.mpl.ird.fr/SiteSGASS/Prugnolle/ClonalityPage.html. The program compares the observed F(IS) of the population with the F(IS) expected if genets (multilocus genotypes present in multiple copies within the population) were chosen randomly from the set of different multilocus genotypes. The randomization procedure is performed with the same number of genets and the same number of repetitions per genet as what is observed in the original data set.
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