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Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates
Published on: March 6, 2019
Eth-oxy-carbonyl-methyl 3-(4-chloro-benzyl-idene)dithio-carbazate
Abstract:
Mol-ecules of the title compound, C(12)H(13)ClN(2)O(2)S(2), are linked into centrosymmetric dimers by pairs of inter-molecular N-H⋯S hydrogen bonds. In the crystal structure, there are π-π stacking inter-actions between symmetry-related benzene rings with a centroid-centroid distance of 3.7305 (13) Å, a perpendicular distance between the planes of 3.2851 (9) Å and a slippage of 1.768 Å. The structure is further stabilized by weak inter-molecular C-H⋯O hydrogen bonds.
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