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Updated: Jun 1, 2026

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
(RS)-1-(1-Acetyl-indolin-5-yl)-2-chloro-propan-1-one
1Department of Chemistry, Guangdong Medical College, Dongguan 523808, People's Republic of China.
Abstract:
The mol-ecule of the title compound, C(13)H(14)ClNO(2), is roughly planar [maximum deviation = 0.060 (2) Å] with the disordered Cl/CH(3) group asymetrically distributed on both sides of the mean plane. Indeed, the Cl and CH(3) located on the stereogenic carbon exchange each other with occupancy factors in the ratio 0.60:0.40. The whole crystal is a racemate. Non-classical C-H⋯O hydrogen bonds and π-π inter-actions [centroid-centroid distance = 3.6959 (9) Å] between symmetry-related phenyl rings stabilize the crystal structure.
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