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Updated: Jun 1, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
(E)-N'-(3-Nitro-benzyl-idene)-4-(8-quinol-yloxy)butano-hydrazide
Li Zeng1, Xiao-Si Zhou, Li-Hua Lv
1Department of Pharmacy, Shaoyang Medical College, Shaoyang, Hunan 422000, People's Republic of China.
Abstract:
In the title Schiff base compound, C(20)H(18)N(4)O(4), the conformation along the bond sequence linking the benzene and quinoline rings is trans-(+)gauche-trans-trans-(+)gauche-trans-trans. The dihedral angle between the aromatic ring systems is 80.3 (6)°. In the crystal, a pair of inter-molecular N-H⋯N hydrogen bonds link the mol-ecules into centrosymmetric R(2) (2)(20) dimers, which are aggregated via π-π inter-actions into sheets [quinoline-benzene ring centroid-centroid separation = 3.572 (2)-3.773 (3) Å].
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The IUPAC and common names of amides are derived from the parent carboxylic acid, by replacing the suffix “oic acid” and “ic acid,” respectively, with “amide.” In the following example, the IUPAC name ethanamide is derived from ethanoic acid, and the common name, acetamide, is obtained from acetic acid.
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